Detection of the antitrichomonal drug nitrimidazine (Naxogin) in urine.
نویسندگان
چکیده
For 10 years vaginal trichomoniasis has been treated by oral chemotherapy. Some cases appear not to respond satisfactorily to the drug used, and it is important to know whether or not the patient is taking the drug, and if so, whether or not it is being absorbed from the alimentary tract. A simple method for detecting these drugs in urine may be of use in such cases. Two antitrichomonal drugs in current use are metronidazole ('Flagyl' May and Baker) and nitrimidazine ('Naxogin' Carlo Erba). Both are derivatives of 5-nitroimidazole (Figs 1 and 2).
منابع مشابه
Nitrimidazine compared with metronidazole in the treatment of vaginal trichomoniasis.
A new substituted nitroimidazole, nitrimidazine (Naxogin), is compared with the established drug, metronidazole (Flagyl), for the treatment of vaginal trichomoniasis in a randomized double-blind trial. Nitrimidazine cured 39 (68%) out of 57 patients and showed no undesirable effects other than nausea in one patient. Metronidazole cured 51 (89%) out of 57 patients and also caused nausea in one p...
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ورودعنوان ژورنال:
- The British journal of venereal diseases
دوره 47 1 شماره
صفحات -
تاریخ انتشار 1971